![]() “Our discovery helps us understand how evolution came up with ways to turn CO 2 and light into oxygen and sugar in bacteria, long before any plants existed on our planet.” Nogales is also a senior faculty scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division. “This work is a breakthrough in the field of photosynthesis,” said Paul Sauer, a postdoctoral researcher in UC Berkeley Professor Eva Nogales’ cryo-EM lab. Nogales discusses the use of cryo-EM to study complex cell biology systems and more on the Cryo-Talk Podcast. As a postdoctoral researcher in the Kerfeld Lab, Domínguez-Martín initiated the study at MSU and brought it to completion at Berkeley Lab. “It’s 12 pages of discoveries,” said María Agustina Domínguez-Martín of the Nature report. The team documented several new findings, including finding a new phycobilisome protein and observing two new ways that the phycobilisome orients its light-capturing rods that hadn’t been resolved before. From Left: Kerfeld, Sutter, Domínguez-Martín, and Sauer. That’s a big advantage,” said Markus Sutter, a senior research associate in the Kerfeld Lab, which operates at MSU and Berkeley Lab, and affiliate scientist in Environmental Genomics and Systems Biology (EGSB). “Once you see how something works, you have a better idea of how you can modify it and manipulate it. “With a blueprint like the one we’ve provided in this study, you can start thinking about tuning and optimizing the light-harvesting component of photosynthesis.” “There’s a lot of interest in using cyanobacteria as solar-powered factories that capture sunlight and convert it into a kind of energy that can be used to make important products,” said Cheryl Kerfeld, a member of the MSU-DOE Plant Research Laboratory, which is supported by the U.S. This animation gives a 360-degree view of the phycobilisome structure researchers helped reveal.
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